Prospect had no answer for Glenbrook South quarterback Mac Zabriske on Friday night in Glenview for both teams' season openers.
Zabriske completed 8 of 12 passes with 1 interception for 148 yards and 4 touchdowns as the Titans defeated the Knights 34-10 at John Davis Stadium in a nonconference game.
New Prospect coach Mike Sebestyen lost his debut as the Knights' head coach after Brent Pearlman stepped down last season.
"The turnovers (3) hurt us," Sebestyen said. "As we talked about, for this team, with the small numbers that we have, we need to be detailed and disciplined. And at times we were not disciplined."
The Knights started out well, taking the opening kick off in the first quarter and taking a 3-0 lead courtesy of Vito Anzalone's 32 yard field goal.
A fumble recovery by the Titans' Gus Shipp led to Zabriske's 9-yard touchdown pass to Zach Jones on the first play of the second quarter for a 7-3 lead.
Following a Knight punt Zabriske tossed a 44 yard TD pass to Sully Stadler for a 13-3 lead with 8:22 left in the first half.
With :54 left in the half Zabriske found Charlie Tisch with a 14 yard scoring pass and a 20-3 lead. B.J. Hoekstra's interception set up the score.
Sophomore running back Sam Mazukelli (14 carries 94 yds.) broke loose on a 44 yard run to make the score 20-10 with 9:34 left in the quarter.
"We just had some unexcusable mistakes," said Sebestyen. "We will learn from them and be better next week. Sam Frasco and Mazukelli had some big runs for us."
Frasco rushed 12 times for 56 yards before being sidline in the third quarter with cramps.